Seminars

ISMB seminars take place on Wednesdays during term time, providing research staff and students with the opportunity to hear talks by world class scientists.

The termly seminar series are organised around specific themes, and are co-ordinated jointly by the Research Department of Structural Molecular Biology at UCL and the Department of Natural Sciences, Birkbeck.

Everyone is welcome to attend.

ISMB Seminar Series Autumn Term 2024-25

Understanding neuronal processes at multiple scales – key questions and new approaches

Series overview:

Neurons are highly-differentiated cells that employ great structural and functional diversity within networks that underlie brain function. However, understanding how these cells function at the molecular level is no small challenge. The autumn seminar series in 2024 will examine how neurons are able to perform complex functions using simple molecular building blocks. The seminar series will include talks on the molecular structure of neurons at different scales assisted by the latest high-resolution imaging approaches. Speakers will also examine the molecular basis of neuronal functions including cytoskeletal trafficking, localised protein synthesis, and circuit formation. In addition, the series will explore how molecular insights may be exploited in the treatment of neurodegenerative diseases.

Coordinators: Matthew Gold and Andres Ramos

All seminars run on Wednesdays between 13:00-14:00.

25th September 2024  

“Engineering” Neuroscience: combining bioengineering, stem cells technologies and in vitro modelling to better understand neurodegeneration
Dr Andrea Serio, The Francis Crick Institute, UK
Host: Prof. Andres Ramos
Venue: Gavin de Beer Lecture Theatre, UCL Anatomy Building
2nd October 2024  

New approaches to understanding and targeting the brain’s greatest gatekeeper: the GABA-A receptor
Dr Paul Miller, University of Cambridge, UK
Host: Prof. Matthew Gold
Venue: MAL 532 (Birkbeck Malet Place building)
9th October 2024  

ERK activation waves coordinate the mechanical cell competition that leads to collective onslaught of bacterially-infected epithelial cells
Dr Effie Bastounis, Tübingen University, Germany
Host: Dr Brian Ho
Venue:  AV Hill Lecture Theatre, UCL Medical Sciences Building
16th October 2024  

Totally wired: amping up the de novo design of bioenergetic protein components
Prof. Ross Anderson, University of Bristol, UK
Host: Prof. Amandine Maréchal
Venue: MAL 532 (Birkbeck Malet Place building)
6th November 2024  

Integrating imaging and omics data with AI to decode neurodegenerative disorders
Dr Raphaëlle Luisier, Idiap Research Institute, Switzerland
Host: Prof. Andres Ramos
Venue: AV Hill Lecture Theatre (LT 131), UCL Medical Sciences Building
13th November 2024  

New insights into the molecular anatomy and dynamics of excitatory synapses
Dr Harold MacGillavry, University of Utrecht, The Netherlands
Host: Prof. Matthew Gold
Venue: MAL 532 (Birkbeck Malet Place building)
20th November 2024  

The neuropeptidergic connectome
Dr William Schafer, MRC Laboratory of Molecular Biology, Cambridge, UK
Host: Prof. Matthew Gold
Venue:  Gavin de Beer Lecture Theatre, UCL Anatomy Building
27th November 2024  

Manipulation of protein quality control systems: from the bench to the clinic and back
Dr Anne Bertolotti, MRC Laboratory of Molecular Biology, Cambridge,  UK
Host: Prof. Andres Ramos
Venue: MAL 532 (Birkbeck Malet Place building)
4th December 2024  

Regulating RNA in space and time in memory circuits
Dr Florence Besse, Institut de Biologie Valrose, France
Host: Prof. Andres Ramos
Venue: Gavin de Beer Lecture Theatre, UCL Anatomy Building
11th December 2024  

Deciphering Known and Unknown Targets for Drug Discovery  
Dr Gabriel Balmus,  UK Dementia Research Institute
Host: UCL Postdocs – Neeladri Sen, Georgina Charlton, Maria Tossounian
Venue: MAL 532 (Birkbeck Malet Place building)

 

Previous ISMB seminars
2023-24 Term3/ Summer: Emerging methods in Biophysics
2023-24 Term2/Spring series: Emergent properties of complex biological systems
2023-24 Term 1/Autumn series: Tying the knot between experiment and computation in Molecular and Cellular Biology

2022-23
2022-23 Term 3/Summer series: Selectivity and Promiscuity in Biomolecular Interactions
2022-23 Term 2/Spring series: Capturing scales of biological mechanisms: from individual molecules to organisms
2022-23 Term 1/Autumn series: Re-organising the Cell

2021-22
2021-22 Term 3/Summer series: Immune Receptors in Health and Disease
2021-22 ISMB Special Event: Two Years of Covid-19
2021-22 Term 2/Spring series: Transcription-coupled processes: gene regulation, DNA repair and recombination in cells and viruses
2021-22 Term 1/Autumn series: RNA, the Multi-Faceted Regulator

2020-21
2020-21 ISMB Special Event: Ancestry, Genetics and Race: Dealing with the Legacy of Scientific Racism
2020-21 Term 3/Summer series: Life at the single-molecule level: from DNA interactions to cell-level processes
2020-21 Term 2/Spring series: Understanding molecular machines: from mechanisms to health and disease
2020-21 Term 1/Autumn series: Redox regulation in health and disease

 

For further information about ISMB Seminars, please contact the ISMB administrator.