Publications

Professor Steven Perkins (Professor of Structural Biochemistry, UCL) made the front cover of October’s Biochemical Journal (vol. 476, issue 19) with his latest paper:

Crystal structure of zinc-α2-glycoprotein in complex with a fatty acid reveals multiple different modes of protein-lipid binding

A joint project with UCL Medicine and the University of Bedfordshire, it is a combination of work done on Professor Perkins’ new analytical ultracentrifuge, protein crystallography and recombinant proteins.

Citation: Lau, A. M., Zahid, H., Gor, J., Perkins, S. J., Coker, A. R. & McDermott, L. C. (2019) Crystal structure of zinc-α2-glycoprotein in complex with a fatty acid reveals multiple different modes of lipid binding. Biochem. J. 476, 2815-2834.

A paper by Professor Neil McDonald’s research group, in collaboration with Sir Richard Treisman, has been published in Nature Cell Biology, identifying a new RPEL-family of rhoGAPs that link Rac/Cdc42 GTP loading to G-actin availability.

The paper is available here.

Professor Bart Hoogenboom’s research group published a paper titled ‘Quantification of Biomolecular Dynamics inside Real and Synthetic Nuclear Pore Complexes using Time-Resolved Atomic Force Microscopy’ in ACS Nano in June 2019.

The full paper is available here.

Professor Frances Brodsky’s research group published a paper titled ‘Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism’ in eLife on 4th June.

The paper is available in full here.