Irilenia Nobeli

The group's current research focus is the analysis of gene expression data produced from high-throughput technologies. We are particularly interested in changes to the transcriptome associated with neurodevelopmental disorders. We are also interested in computational methods for exploring the roles of non-coding RNA in health and disease.

In parallel, our group has a long-standing interest in applying chemoinformatics methods to analyse endogenous metabolites in model organisms and to compare their structure and physicochemical properties to those of exogenous compounds, such as drugs. Our aim is to understand the roles small molecules play in an organism, through prediction of their interactions with proteins using molecular modelling approaches.