Welcome to the Institute of Structural and Molecular Biology

The ISMB thrives on scientific excellence and research integrity within a supportive culture of inclusion and diversity. The institute coordinates UCL's and Birkbeck's strategy in our fields of scientific enquiry. The ISMB was founded in 2003 to promote multi-disciplinary research at the interface of structural-, computational- and chemical biology at UCL and Birkbeck. Since then, we have become one of the internationally premier institutions in multidisciplinary life sciences. Scientists at UCL and Birkbeck work hand-in-hand to deliver our mission, to push the frontiers of science and to communicate our discoveries in research-led teaching. Our research portfolio encompasses several foci, including (i) gene expression & RNA biology, (ii) protein folding, membranes & trafficking, (iii) microbiology & synthetic biology, (iv) metabolism, cancer & biological chemistry and (v) evolution, AI & deep learning. Our activities are supported by our host institutions and generous support from the Research Councils UK as well as key global charities including the Wellcome Trust. We are fortunate to harbour sophisticated high-end instrumentation including cryogenic electron microscopy and electron tomography, nuclear magnetic resonance, mass spectrometry, and single-molecule biophysics that play a pivotal role in enableing our aims and objectives.

I would like to invite you to visit and learn more about our research and teaching activities, our brilliant staff and high-calibre technical facilities, and last but least to join us in our range of seminars, subject specific clubs, and symposia, most of which have moved online for the duration of the Covid-19 crisis.








Franca Fraternali, Director of the ISMB