Dr Giulia Zanetti’s research group has been awarded two new grants.
A European Research Council (ERC) Starting Grant was awarded for a project which shows how coat assembly can deliver the flexibility necessary to accommodate a wide variety of cargo proteins, and how the process can be regulated. Her focus is on COPII coat, which mediates export from the endoplasmic reticulum (ER) of about a third of newly synthesized proteins. The aim of the project is to understand the molecular interactions between coat components and understand their role in determination of coat architecture and membrane shape.
Full details are available here.
A Biotechnology and Biological Sciences Research Council (BBSRC) grant was awarded for another project whose overall objective is to dissect the molecular mechanisms involved in COPII coat budding, and in particular to assess the dynamic regulation of the various levels of coat assembly and its role in flexible membrane remodelling.
Further details of Dr Zanetti’s research can be found on her lab website.