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Structural biology programme

The structural biology programme of the ISMB assembles a group of PIs interested in using structural biology approaches as tools to elucidate the molecular basis of protein function and activity. Our vast spectrum of structural investigation techniques include high resolution electron microscopy, x-ray crystallography, and NMR.

PIs in the Structural Biology programme of the ISMB not only benefit from state-of-the-art equipment that cover the entire spectrum of structure determination methods, but also from the unique interdisciplinary environment that the ISMB offers by linking its research programmes.

Programme leader
Professor Helen Saibil

Research facilities
The ISMB has state of the art facilities in electron microscopy, x-ray crystallography and NMR.

Electron Microscopy Dr LuChun Wang
X-ray Crystallography Dr Ambrose Cole
NMR Dr Angelo Miguel Figueiredo






A mutant chaperonin with rearranged inter-ring electrostatic contacts and temperature-sensitive dissociation. Sewell, BT, Best, RB, Chen, S, Roseman, AM, Farr, GW, Horwich, AL & Saibil, HR (2004) Nature Struct. Mol. Biol. 11, 1128-1133.

Institute of Structural Molecular Biology, University of London
Last modifi
ed in 2007 by
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