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| Programme |
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Time: 09.30-17.00 on Monday 19 and Tuesday 20 June.
Venue: Lecture Theatre 1, Cruciform Building, UCL, Gower Street, London
Places for the Symposium are limited.
There is no charge to attend but to register for this event please send an email to t.hoe@mail.cryst.bbk.ac.uk by 16.00 on Thursday 15 June.
**Download the latest programme and directions here **
Note: Lunch is not included in the Symposium arrangement but there are many sandwich shops, cafes and restaurants nearby. |
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| - Day 1 - Monday 19 June |
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| A welcome to the ISMB Symposium |
09.30 – 09.35
Introduction by David Latchman, Master of Birkbeck |
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| Chemical Biology Programme |
09.35 – 10.20
'Molecular Basis for Increased Susceptibility of Isolates with Atazanavir Resistance-Conferring Substitution I50L to Other Protease Inhibitors'
Michael Doyle, Bristol-Myers Squibb, USA |
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10.20 – 11.05
'Diversity Oriented Synthesis and the Small Molecule Approach to Chemical Biology'
Steve Caddick, Institute of Structural Molecular Biology, UK |
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11.05 – 11.30
Tea and coffee break in the South Cloisters, UCL |
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11.30 – 12.20
Chemical Genetic Dissection of Kinase Pathways in Disease and Normal Physiology
Kevan Shokat, University of California, San Francisco, USA |
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12.20 - 14.00
Lunch break |
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| Biophysics Programme |
14.00 – 14.45
'Single myosins pulling on membranes'
Justin Molloy, NIMR, UK |
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14.45 – 15.30
'Synchrotron Radiation Circular Dichroism Spectroscopy: Applications in Structural and Functional Genomics'
Bonnie Wallace, ISMB , UK |
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15.30 – 16.00
Break |
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16.05 – 16.50
'On DNA Replication by the T4 Replisome'
Steve Benkovic, Pennsylvania State University, USA |
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| - Day 2 - Tuesday 20 June |
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| Bioinformatics Programme |
09.30 – 10.15
Exploiting Structural and Comparative Genomics to Reveal Protein Functions
Christine Orengo, Institute of Structural Molecular Biology, UK |
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10.15 – 11.00
De-novo prediction of protein structure from ideal Forms
Willie Taylor, NIMR, UK |
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11.00 – 11.30
Break |
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| Proteomics Programme |
11.30 – 12.15
Ultra-High Sensitivity Proteomics
Jasminka Godovac-Zimmerman, ISMB, UK |
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12.15 – 13.05
Defining the structure and function of macromolecular complexes
Brian Chait, Rockefeller – New York, USA |
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13.05 - 14.30
Lunch break |
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| Structural Biology Programme |
14.30 – 15.15
Cryo-electron tomography illustrates the mechanism of HIV-1 Core Assembly
Stephen Fuller, University of Oxford, UK |
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15.15 – 16.00
Of H1 and N1
John Skehel, NIMR, UK
[Speaker profile available here] |
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16.00 – 16.30
Tea and coffee break, South Cloisters, UCL |
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16.30 – 17.20
Motions in Macromolecular Machines
Tom Steitz, Yale University, USA |
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| Concluding remarks |
17.20 – 17.25
Malcolm Grant, Provost of UCL |
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