About the Institute of Structural Molecular Biology
The 2nd ISMB symposium ‘At the interface of Structural Biology, Chemical Biology, Bioinformatics, Biophysics and Proteomics’ will be held on Monday 19 June and Tuesday 20 June. *****

The latest programme is available below. Sir John Skehel, FRS is one of the speakers at the ISMB Symposium - a profile of this speaker is now available.

Time: 09.30-17.00 on Monday 19 and Tuesday 20 June.
Venue: Lecture Theatre 1, Cruciform Building, UCL, Gower Street, London

Places for the Symposium are limited.
There is no charge to attend but to register for this event please send an email to t.hoe@mail.cryst.bbk.ac.uk by 16.00 on Thursday 15 June.

**Download the latest programme and directions here **

Note: Lunch is not included in the Symposium arrangement but there are many sandwich shops, cafes and restaurants nearby.
- Day 1 - Monday 19 June
A welcome to the ISMB Symposium
09.30 – 09.35
Introduction by David Latchman, Master of Birkbeck
Chemical Biology Programme
09.35 – 10.20
'Molecular Basis for Increased Susceptibility of Isolates with Atazanavir Resistance-Conferring Substitution I50L to Other Protease Inhibitors'
Michael Doyle, Bristol-Myers Squibb, USA
10.20 – 11.05
'Diversity Oriented Synthesis and the Small Molecule Approach to Chemical Biology'
Steve Caddick,
Institute of Structural Molecular Biology, UK
11.05 – 11.30
Tea and coffee break in the South Cloisters, UCL
11.30 – 12.20
Chemical Genetic Dissection of Kinase Pathways in Disease and Normal Physiology
Kevan Shokat,
University of California, San Francisco, USA
12.20 - 14.00
Lunch break
Biophysics Programme
14.00 – 14.45
'Single myosins pulling on membranes'
Justin Molloy
14.45 – 15.30
'Synchrotron Radiation Circular Dichroism Spectroscopy: Applications in Structural and Functional Genomics'
Bonnie Wallace, ISMB , UK
15.30 – 16.00
16.05 – 16.50
'On DNA Replication by the T4 Replisome'
Steve Benkovic, Pennsylvania State University, USA
- Day 2 - Tuesday 20 June
Bioinformatics Programme
09.30 – 10.15
Exploiting Structural and Comparative Genomics to Reveal Protein Functions
Christine Orengo
, Institute of Structural Molecular Biology, UK
10.15 – 11.00
De-novo prediction of protein structure from ideal Forms
Willie Taylor
11.00 – 11.30
Proteomics Programme
11.30 – 12.15
Ultra-High Sensitivity Proteomics
Jasminka Godovac-Zimmerman, ISMB, UK
12.15 – 13.05
Defining the structure and function of macromolecular complexes
Brian Chait, Rockefeller – New York, USA
13.05 - 14.30
Lunch break
Structural Biology Programme
14.30 – 15.15
Cryo-electron tomography illustrates the mechanism of HIV-1 Core Assembly
Stephen Fuller,
University of Oxford, UK
15.15 – 16.00
Of H1 and N1
John Skehel, NIMR, UK
[Speaker profile available here]
16.00 – 16.30
Tea and coffee break, South Cloisters, UCL
16.30 – 17.20
Motions in Macromolecular Machines
Tom Steitz, Yale University, USA
Concluding remarks
17.20 – 17.25
Malcolm Grant, Provost of UCL



Institute of Structural Molecular Biology, University of London
Last modifi
ed 2006 by t.hoe@ismb.lon.ac.uk