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Programme | Day 1 | Thursday 3 June
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Welcome and introductions |
| 09.30 - 09.35 |
Opening comments and welcome |
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Malcolm Grant, Provost of UCL |
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| 09.35 - 09.40 |
The Institute of Structural Molecular Biology |
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Gabriel Waksman, ISMB Director |
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Structural Biology Programme |
| 09.40 - 10.30 |
Phosphoinositide binding domains: High fyve for NMR |
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Michael Overduin, University of Birmingham, UK |
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| 10.30 - 11.20 |
Mechanics of chaperonin action |
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Helen Saibil, Birkbeck College, UK |
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| 11.20 - 11.50 |
Tea and coffee break |
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| 11.50 - 12.50 |
Structural Analysis of the Mechanism of DNA Polymerase Sliding Clamp and Clamp Loaders |
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John Kuriyan, University of California Berkeley, USA |
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Chemical Biology Programme |
| 14.00 - 14.50 |
SMART Drug Design: Novel Small Molecule Inhibitors of the Oncogenic Protein Kinase Src |
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Tomi Sawyer, ARIAD Pharmaceuticals, USA |
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| 14.50 - 15.40 |
Non-Viral Gene Delivery Vectors |
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Helen Hailes, UCL, UK |
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| 15.40 - 16.00 |
Tea and coffee break |
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| 16.00 - 17.00 |
Chemical Biology of Protein Lipidation |
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Herbert Waldmann, Max Planck Institute, Germany |
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Programme | Day 2 | Friday 4 June
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Welcome and introduction for the second day |
| 09.30 - 09.35 |
Opening comments and welcome |
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David Latchman, Master of Birkbeck College |
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Biophysics Programme |
| 09.35 - 10.25 |
Adaptive Ligands: A New Design Paradigm |
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Ernesto Freire, Johns Hopkins University, USA |
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| 10.25 - 11.15 |
Searching for Specificity in Tyrosine Kinase-Mediated Signal Transduction |
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John Ladbury, UCL, UK |
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| 11.15 - 11.45 |
Tea and coffee break |
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| 11.45 - 12.45 |
From Fundamental Protein Folding to Novel Therapies for Cancer |
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Alan Fersht, University of Cambridge, UK |
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Bioinformatics Programme |
| 14.00 - 14.50 |
Shedding Light on GPCR Signal Transduction |
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Garland Marshall, Washington University, USA |
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| 14.50 - 15.40 |
Predicting novel folds for globular and membrane proteins |
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David Jones, UCL, UK |
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| 15.40 - 16.10 |
Tea and coffee break |
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| 16.10 - 17.10 |
Inferring Protein Function from 3D Structure |
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Janet Thornton, EBI, UK |
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| 17.10 - 17.15 |
Concluding remarks |
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Gabriel Waksman, ISMB Director |