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Structural biology programme
The structural biology programme of the ISMB assembles a group of PIs interested in using structural biology approaches as tools to elucidate the molecular basis of protein function and activity. Our vast spectrum of structural investigation techniques include high resolution electron microscopy, x-ray crystallography, and NMR.
PIs in the Structural Biology programme of the ISMB not only benefit from state-of-the-art equipment that cover the entire spectrum of structure determination methods, but also from the unique interdisciplinary environment that the ISMB offers by linking its research programmes.
Programme leader
Professor Helen Saibil
Research facilities
The ISMB has state of the art facilities in electron microscopy, x-ray crystallography and NMR.
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A mutant chaperonin with rearranged inter-ring electrostatic contacts and temperature-sensitive dissociation. Sewell, BT, Best, RB, Chen, S, Roseman, AM, Farr, GW, Horwich, AL & Saibil, HR (2004) Nature Struct. Mol. Biol. 11, 1128-1133.
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