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Principal Publications


A. Ilangovan, CWM. Kay, S Roier, H. El Mkami, E. Salvadori, EL. Zechner, G Zanetti, G.Waksman (2017). Cryo-

EM structure of a relaxase reveals the molecular basis of DNA unwinding during bacterial conjugation. Cell.

169 (4): 708–721.e12


TR. Costa, A. Ilangovan, M. Ukleja, A. Redzej, JM. Santini, TK. Smith, EH. Egelman, G. Waksman (2016).

Structure of the Bacterial Sex F Pilus Reveals an Assembly of a Stoichiometric Protein-Phospholipid Complex.

Cell. 166(6):1436-1444.e10


M. Hospenthal, A. Redzej, K. Dodson, M. Ukleja, B. Frenz, C. Rodrigues, S. Hultgren, F. DiMaio, E. Egelman

and G. Waksman (2016). Structure of a Chaperone-Usher Pilus Reveals the Molecular Basis of Rod Uncoiling.

Cell. 164:269-278.

4. HH.Low , F. Gubellini, A. Rivera-Calzada, N. Braun, S. Connery, A. Dujeancourt, F. Lu, A. Redzej, R. Fronzes, EV. Orlova, G. Waksman (2014) Structure of a type IV secretion system. Nature. 2014 Apr 24;508(7497):550-3. doi: 10.1038/nature13081. Epub 2014 Mar 9. PMID: 24670658 5. S. Geibel, E. Procko, S.J. Hultgren, D. Baker, and G. Waksman (2013) Structure and energetic basis of folded protein transport by the FimD usher. Nature. 496:243-246. 6. G. Phan, H. Remaut, T.Wang, W. Allen, K. Pirker, A. Lebedev, N. Henderson, S. Geibel, E. Volkan, J. Yan, M. Kunze, J. Pinkner, B. Ford, C. Kay, H. Li, S. Hultgren, D. Thanassi, and G. Waksman (2011) Crystal structure of the FimD usher bound to its cognate FimC:FimH substrate. Nature. 474:49-53. 7. Chandran, R. Fronzes, S. Duquerroy, N. Cronin, J. Navaza, and G. Waksman (2009) Crystal structure of the outer membrane complex of a type IV secretion system. Nature. 462:1011-1015. 8. R. Fronzes, E. Schaefer, H. Saibil, E. Orlova and G. Waksman (2009) Structure of type IV secretion core complex. Science. 323:266-268. 9. H. Remaut, C. Tang, N.S. Henderson, J.S. Pinkner, T. Wang, S.J. Hultgren, D.G. Thanassi, G. Waksman, H. Li (2008) Fiber Formation Across the Bacterial Outer Membrane by the Chaperone/Usher Pathway. Cell. 133:640-652. First author (H. Remaut) member of the Waksman lab 10. F. G. Sauer, J. Pinkner, G. Waksman, and S.J.Hultgren (2002) Chaperone Priming of Pilus Subunit Facilitates a Topological Transition that Drives Fiber Formation. Cell. 111:543-51. Waksman sole corresponding author 11. K.W. Dodson, J.S. Pinkner, T. Rose, G. Magnusson, S.J. Hultgren, and G. Waksman (2001) Structural Basis of Tropism of Pyelonephritic /E. coli/ for the Human Kidney. Cell. 105:733–743. 12. F.G. Sauer, K. Fütterer, J.S. Pinkner, K.W. Dodson, S.J. Hultgren, and G. Waksman (1999) Structural basis of chaperone function and pilus biogenesis. Science. 285:1058-1061. 13. S. Korolev, J. Hsieh, G. Gauss, T.M. Lohman, and G. Waksman (1997) Major domain swivelling revealed by the crystal structure of binary and ternary complexes of /E.coli/ Rep helicase bound to single-stranded DNA and ADP. Cell. 90:635-647. 14. D. Ornitz, A. Herr, M. Nillson, J. Westman, C-M. Svahn, and G. Waksman (1995) FGF binding and FGF receptor activation by synthetic heparan-derived di- and trisaccharides. Science. 268:432-436. 15. G. Waksman, S. Shoelson, N. Pant, D. Cowburn, and J. Kuriyan. (1993) Binding of a high affinity phosphotyrosyl peptide to the src SH2 domain: crystal structures of the complexed and peptide-free forms. Cell. 72:779-790. 16. G. Waksman, D. Kominos, S. Robertson, N. Pant, D. Baltimore, R.Birge, D. Cowburn, H. Hanafusa, B. Mayer, M. Overduin, M. Resh, C. Rios, L. Silverman and J. Kuriyan (1992) Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides. Nature. 358:646-653.