Chemical biology programme

Laboratories participating in the Chemical Biology programme focus on the application of chemistry to the investigation of biological macromolecules and macromolecular interactions. Structural biology contributes essential information about the chemistry of the interfaces of interacting proteins. This information can in turn be exploited for the design of reagents interfering with or disrupting macromolecular interactions. On this basis, we design synthetic proteins and reagents, which can be used to provide a better understanding of biological processes.

Programme leader
Professor Helen Hailes





3D structure of apoNCS bound to a non-natural ligand.

Institute of Structural Molecular Biology, University of London, ismb-admin@
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